李田, 博士, 副教授, 硕士生导师
Tian LI, Ph.D.
Associate Professor
State Key Laboratory of Silkworm Genome Biology
Institute of Sericulture and Systems Biology, Southwest University
Email: lit{at}swu.edu.cn
Phone: +86-23-68251088
Fex: +86-23-68251128
ORCID iD iconorcid.org/0000-0003-4362-0130

EDUCATION AND WORK EXPERIENCE:

  • 2014-2015 Visting Scholar TROEMEL Lab, Division of Biological Science, University of California, San Diego.
  • 2014 Associate Professor State Key Laboratory of Silkworm Genome Biology, and Institute of Sericulture and Systems Biology, Southwest University, China.
  • 2009 Lecturer State Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, Southwest University, China.
  • 2009 Ph.D. Biochemistry and Molecular Biology (Supervisor: Prof. Zeyang Zhou), Institute of Sericulture and Systems Biology, Southwest University, China.
  • 2005 M.S. Microbiology (Supervisor: Prof. Zeyang Zhou), Institute of Sericulture and Systems Biology, Southwest University, China.
  • 2003 B.Sc. Animal Medicine, College of Animal Science and Technology, Southwest Agricultral University, China.
  • 2003 B.Sc. Computer Science and Technology, College of Computer and Information, Southwest Agricultral University, China.

RESEARCH INTERESTS:

  • Pathogen-host interactions
    • How does pathogen infect host?
    • How does host respond to infection?
  • Genomics and comparative genomics
    • Functional genomics.
    • Evolution of genomes.
  • Bioinformatics

SUPPORTS:

  • Natural Scientific Fund, China (31772678) 2018 – 2021
  • Natural Scientific Fund, China (31472151) 2015 – 2018
  • Fundamental Research Funds for the Central Universities (XDJK2015A010) 2015 – 2017
  • Natural Scientific Fund, China (31001036) 2010 – 2013
  • Natural Scientific Fund, China (30930067) 2010 – 2013
  • Chongqing Natural Science Foundation (CSTC, 2010BB1139) 2010 – 2013
  • Fundamental Research Funds for the Central Universities (XDJK2009C148) 2010 – 2012
  • The Research Fund for the Doctoral Program, (SWU109039) 2009

PUBLICATIONS:

  1. Kun Lu, Tian Li, Jian He, Wei Chang, Rui Zhang, Miao Liu, Mengna Yu, Yonghai Fan, Jinqi Ma, Wei Sun, Cunmin Qu, Liezhao Liu, Nannan Li, Ying Liang, Rui Wang, Wei Qian, Zhanglin Tang, Xinfu Xu, Bo Lei, Kai Zhang, Jiana Li. qPrimerDB: a thermodynamics-based gene-specific qPCR primer database for 147 organisms. Nucleic Acids Research, 2017, gkx725. [PDF]. (Authors contributed equally to this paper.)
  2. Tian Li, Guo-Qing Pan, Charles R. Vossbrinck, Jin-Shan Xu, Chun-Feng Li, Jie Chen, Meng-Xian Long, Ming Yang, Xiao-Fei Xu, Chen Xu, Bettina A. Debrunner-Vossbrinck, Ze-Yang Zhou. SilkPathDB: a comprehensive resource for the study of silkworm pathogens. Database. 2017(1): bax001. [PubMed] [PDF]
  3. Donglin Yang, Lixia Pan, Pai Peng, Xiaoqun Dang, Chunfeng Li, Tian Li, Mengxian Long, Jie Chen, Yujiao Wu, Huihui Du, Bo Luo, Yue Song, Rui Tian, Jie Luo, Zeyang Zhou and Guoqing Pan. Interaction between SWP9 and Polar Tube Proteins of the Microsporidian Nosema bombycis and Function of SWP9 as a Scaffolding Protein Contribute to Polar Tube Tethering to the Spore Wall. Infect Immun. 2017, 85(3), pii: e00872-16. [PubMed] [PDF]
  4. Bing Han, Kang Zhou, Zhihong Li, Bin Sun, Qi Ni, Xianzhi Meng, Guoqing Pan, Chunfeng Li, Mengxian Long, Tian Li, Congzhao Zhou, Weifang Li, Zeyang Zhou. Characterization of the First Fungal Glycosyl Hydrolase Family 19 Chitinase (NbchiA) from Nosema bombycis (Nb). J Eukaryot Microbiol. 2016, 63(1):37-45. doi: 10.1111/jeu.12246. [PubMed]
  5. Huihui Du, Rendong Fang, Tingting Pan, Tian Li, Nengzhang Li, Qiang He, Rui Wu, Yuanyi Peng, and Zeyang Zhou. Comparative genomics analysis of two different virulent bovine Pasteurella multocida isolates. International Journal of Genomics. 2016(2016), accepted. http://dx.doi.org/10.1155/2016/4512493. [Link]
  6. Xu J, He Q, Ma Z, Li T, Zhang X, Debrunner-Vossbrinck BA, Zhou Z, Vossbrinck CR. The Genome of Nosema sp. Isolate YNPr: A Comparative Analysis of Genome Evolution within the Nosema/Vairimorpha Clade. PLoS One. 2016, 11(9):e0162336. doi: 10.1371/journal.pone.0162336. [PubMed]
  7. Qiwei Zeng, Hongyu Chen, Chao Zhang, Minjing Han, Tian Li, Xiwu Qi, Zhonghuai Xiang, Ningjia He. Definition of Eight Mulberry Species in the Genus Morus by Internal Transcribed Spacer-Based Phylogeny. PLoS One. 2015, 10(8):e0135411. doi: 10.1371/journal.pone.0135411. eCollection 2015. [PubMed]
  8. Ma B, Li T, Xiang Z, He N. MnTEdb, a collective resource for mulberry transposable elements. DATABASE. 2015, pii: bav004. doi: 10.1093/database/bav004. [PubMed]
  9. Liu T, Xu J, Luo B, Chen J, Li Z, Li T, Pan G, Li X, Zhou Z. Nosema sp. PM-1, a new isolate of microsporidian from infected Papilio machaon Linnaeus, based on ultrastructure and molecular identification. Acta Parasitol. 2015, 60(2): 330-336.
  10. Wang Y, Dang X, Luo B, Li C, Long M, Li T, Li Z, Pan G, Zhou Z. Characterization of a novel otubain-like protease with deubiquitination activity from Nosema bombycis (Microsporidia). Parasitol Res. 2015. [Epub ahead of print].
  11. Wang Y, Dang X, Ma Q, Liu F, Pan G, Li T, Zhou Z.Characterization of a novel spore wall protein NbSWP16 with proline-rich tandem repeats from Nosema bombycis (microsporidia). Parasitology. 2014, 3:1-9. [PubMed]
  12. Tian Li, Xiwu Qi, Qiwei Zeng, Zhonghuai Xiang, Ningjia He. MorusDB: A resource for mulberry genomics and genome biology. DATABASE. 2014, bau054, doi: 10.1093/database/bau054. [PubMed]
  13. Bo Luo, Handeng Liu, Guoqing Pan, Tian Li, Zeng Li, Xiaoqun Dang, Tie Liu, Zeyang Zhou. Morphological and molecular studies of Vairimorpha necatrix BM, a new strain of the microsporidium V. necatrix (microsporidia, burenellidae) recorded in the silkworm, Bombyx mori. Exp Parasitol. 2014, pii: S0014-4894(14)00115-5. doi: 10.1016/j.exppara.2014.05.001. [PubMed]
  14. Xiang H, Zhang R, De Koeyer D, Pan G, Li T, Liu T, Zhou Z. New evidence on the relationship between Microsporidia and Fungi: a genome-wide analysis by DarkHorse software. Can J Microbiol. 2014, 14:1-12. [PubMed]
  15. Zhengang Ma, Chunfeng Li, Guoqing Pan, Zhihong Li, Bing Han, Jinshan Xu, Xiqian Lan, Jie Chen, Donglin Yang, Quanmei Chen, Qi Sang, Xiaocun Ji, Tian Li, Mengxian Long, Zeyang Zhou. 2013. Genome-wide transcriptional response of silkworm (Bombyx mori) to infection by the microsporidian Nosema bombycis. PloS ONE. 2013, 8(12): e84137. [PubMed]
  16. Chen J, Geng L, Long M, Li T, Li Z, Yang D, Ma C, Wu H, Ma Z, Li C, Pan G, Zhou Z. Identification of a novel chitin-binding spore wall protein (NbSWP12) with a BAR-2 domain from Nosema bombycis (microsporidia). Parasitology. 2013, 140(11): 1394-402.
  17. Yang D, Dang X, Tian R, Long M, Li C, Li T, Chen J, Li Z, Pan G, Zhou Z. Development of an approach to analyze the interaction between Nosema bombycis (microsporidia) deproteinated chitin spore coats and spore wall proteins. J Invertebr Pathol. 2013, pii:S0022-2011(13)00149-3.
  18. LI Zhi-Hong, MA Zhen-Gang, LI Wan-Jun, LIU Jun, HAN Bing, LI Tian, PAN Guo-Qing, LI Chun-Feng, ZHOU Ze-Yang. Analysis and Identification of the Differentially Expressed Hemolymph Proteins of Silkworm (Bombyx mori) Infected by Nosema bombycis. Science of Sericulture. 2013, 39(5): 95-101.
  19. GENG Li-Na, WU Hai-Jing, LIU Ting, TIAN Rui, LI Tian, PAN Guo-Qing, ZHOU Ze-Yang. Two-dimensional Electrophoresis Analysis of Nosema bombycis Spore Coat Proteins Prepared by Germination Method and Glas Beads Breaking Method. Science of Sericulture. 2013, 39(5): 0928-0934.
  20. LUO Jie, DENG Yuan-Hong, HUANG Wei, LI Tian, YANG Qiong, YIN Mei, PAN Guo-Qing, LI Chun-Feng, ZHOU Ze-Yang. Sequence Analysis and Subcellular Localization of a Novel Nosema bombycis Gene in Saccharomyces cerevisiae Cells. Science of Sericulture. 2013, 39(2): 0302-0309.
  21. He N, Zhang C, Qi X, Zhao S, Tao Y, Yang G, Lee TH, Wang X, Cai Q, Li D, Lu M, Liao S, Luo G, He R, Tan X, Xu Y, Li T, Zhao A, Jia L, Fu Q, Zeng Q, Gao C, Ma B, Liang J, Wang X, Shang J, Song P, Wu H, Fan L, Wang Q, Shuai Q, Zhu J, Wei C, Zhu-Salzman K, Jin D, Wang J, Liu T, Yu M, Tang C, Wang Z, Dai F, Chen J, Liu Y, Zhao S, Lin T, Zhang S, Wang J, Wang J, Yang H, Yang G, Wang J, Paterson AH, Xia Q, Ji D, Xiang Z. Draft genome sequence of the mulberry tree Morus notabilis. Nat Commun. 2013, 4:2445. doi: 10.1038/ncomms3445.
  22. LI Tian, QI Xiao-Ran, TAO Mei-Lin, LIU Xian-Lin, KANG Ding-Rong, QIN Guo-Wei, PAN Guo-Qing, ZHOU Ze-Yang. A Comparative Genomics Analysis of Secreted Proteins from Four Microsporidia. Science of Sericulture. 2013, 39(3): 0527-0536.
  23. Guoqing Pan*, Jinshan Xu*, Tian Li*, Qingyou Xia, Shao-Lun Liu, Guojie Zhang, Songgang Li, Chunfeng Li, Handeng Liu, Liu Yang, Tie Liu, Xi Zhang, Zhengli Wu, Wei Fan, Xiaoqun Dang, Heng Xiang, Meilin Tao, Yanhong Li, Junhua Hu, Zhi Li, Lipeng Lin, Jie Luo, Lina Geng, LinLing Wang, Mengxia Long, Yongji Wan, Ningjia He, Ze Zhang, Cheng Lu, Patrick J Keeling, Jun Wang, Zhonghuai Xiang and Zeyang Zhou. Comparative genomics of parasitic silkworm microsporidia reveal an association between genome expansion and host adaptation. BMC Genomics. 2013, 14: 186. (*Co-first authors).
  24. Dang X, Pan G, Li T, Lin L, Ma Q, Geng L, He Y, Zhou Z. Characterization of a subtilisin-like protease with apical localization from microsporidian Nosema bombycis. J Invertebr Pathol. 2013, 112(2): 166-174.
  25. LI Tian, LIU Xian-Lin, HAN Bing, QI Xiao-Ran, DANG Xiao-Qun, KANG Ding-Rong, PAN Guo-Qing, ZHOU Ze-Yang. A Genome-wide Prediction and Analysis on Secreted Proteins of Nosema bombycis. Science of Sericulture. 2013, 39(2): 0295-0301.
  26. MA Qiang, LI Tian, DANG Xiao-Qun, PAN Guo-Qing, XU Jing-Shan, ZHOU Ze-Yang. A Method Suitable for Extracting Membrane Protein from Nosema bombycis. Science of Sericulture. 2013, 39(2): 0319 – 0323.
  27. GENG Li-Na, WU Hai-Jing, MA Cheng, LIU Ting, DANG Xiao-Qun, QI Xiao-Ran, LI Tian, PAN Guo-Qing, ZHOU Ze-Yang. Comparative Analysis of Gene Sequences of Related Enzymes in O-mannosylation Pathway of Microsporidian. Science of Sericulture. 2012, 38(03): 158-168.
  28. Lin L, Pan G, Li T, Dang X, Deng Y, Ma C, Chen J, Luo J, Zhou Z. The protein import pore Tom40 in the Microsporidian Nosema bombycis. J Eukaryot Microbiol. 2012, 59(3):251-257.
  29. Handeng Liu, Guoqing Pan, Tian Li, Wei Huang, Bo Luo, Zeyang Zhou. Ultrastructure, chromosomal karyotype, and molecular phylogeny of a new isolate of microsporidian Vairimorpha sp. BM (Microsporidia, Nosematidae) from Bombyx mori in China. Parasitol Res. 2012, 110(1):205-210.
  30. Zhi Li, Guoqing Pan, Tian Li, Wei Huang, Jie Chen, Lina Geng, Donglin Yang, Linling Wang, Zeyang Zhou. SWP5, A Novel Spore Wall Protein Interaction with Polar Tube in the Parasite Nosema bombycis (Microsporidia). Eukaryotic Cell. 2011, 11: 229-237.
  31. Xiang H, Pan G, Zhang R, Xu J, Li T, Li W, Zhou Z, Xiang Z. Natural selection maintains the transcribed LTR retrotransposons in Nosema bombycis. J Genet Genomics. 2010, 37: 305-314.
  32. Tian Li, Xiaoqun Dang, Jinshan Xu, Handeng Liu, Guoqing Pan, Zeyang Zhou. Mitochondrial Pyruvate Dehydrogenase E1 of Nosema bombycis – a Marker in Microsporidian Evolution. Current Zoology. 2009, 55: 423-429.
  33. LI Tian, PAN Guo-Qing, DANG Xiao-Qun, ZHOU Ze-Yang. cDNA Library Construction and EST Analysis of Bombyx mori Silk Gland Heavily Infected byNosema bombycis. Science of Sericulture. 2009, 35(2): 320-327.
  34. Xia Q, Zhou Z, Lu C, Cheng D, Dai F, Li B, Zhao P, Zha X, Cheng T, Chai C, Pan G, Xu J, Liu C, Lin Y, Qian J, Hou Y, Wu Z, Li G, Pan M, Li C, Shen Y, Lan X, Yuan L, Li T, Xu H, Yang G, et al. A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science. 2004, 306: 1937-1940.

Last update: Nov 08, 2017.